任充华 Ren Chonghua

副教授

华南师范大学 生命科学学院

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学术   ACADEMIC

个人简介

任充华,男,山东泰安人,于2019年初作为青年拔尖人才引进到华南师范大学生命科学学院昆虫科学与技术研究所,聘副教授岗位。作为第一作者(含共一)在Trends in Biotechnology, Nucleic Acids Research, Cellular and Molecular Life Sciences (2), Nature Communication等国际刊物上发表论文多篇;主持国家自然科学基金青年项目和博士后基金各一项。目前的主要研究方向为昆虫发育的表观及遗传调控。

教育经历

2017.03-2019.02 华南师范大学, 师资博士后,出站

2014.11-2016.09 美国加州大学戴维斯分校 (UC Davis),博士联合培养

2011.09-2016.12 西北农林科技大学, 硕博连读,获博士学位

2007.09-2011.06 西北农林科技大学, 本科,获学士学位

社会服务

广东省昆虫学会会员

Elsevier出版集团丛书审稿人

Nucleic Acids Research, Scientific Reporters, Frontiers in GeneticsBiochemistry SCI期刊审稿人

主持科研项目

利用德国小蠊基因编辑技术研究CYP15基因功能演化和保幼激素合成进化(31702055),国家自然科学基金青年项目,26万,主持人:任充华,2018-2020

美洲大蠊断肢再生分子机制研究 (2017M622724),中国博士后科学基金面上资助,5万,主持人:任充华,2018-2019

代表性期刊论文

(1) Chonghua Ren, Kun Xu, David Jay Segal, Zhiying Zhang. Strategies for the enrichment and selection of genetically modified cells. Trends in Biotechnology. 37(1) 2019 pp. 58-73 (JCR: Q1, Top, 5/232, IF=13.578)

(2) Sheng Li#, Shiming Zhu#, Qiangqiang Jia#, Dongwei Yuan#, Chonghua Ren#, Kang Li, Suning Liu, Yingying Cui, Haigang Zhao, Yanghui Cao, Gangqi Fang, Daqi Li, Xiaoming Zhao, Jianzhen Zhang, Qiaoyun Yue, Yongliang Fan, Xiao-Qiang Yu, Qili Feng, and Shuai Zhan. The genomic and functional landscapes of developmental plasticity in the American cockroach. Nature Communications. 2018. DOI: 10.1038/s41467-018-03281-1 (共同第一作者) (JCR: Q1, IF=12.353)

(3) Chonghua Ren, Alexa Adams, Benjamin Pyles, Barbara J. Bailus, Henriette O’Geen, David J. Segal. In-vivo applications of cell-penetrating zinc finger transcription factors. In: Liu J. (eds) Zinc Finger Proteins. Methods in Molecular Biology, vol 1867. Humana Press, New York, NY ISBN:978-1-4939-8799-3

(4) Henriette O’Geen#, Chonghua Ren#, Charles M. Nicolet, Andrew A. Perez, Julian Halmai, Victoria M. Le, Joel P. Mackay, Peggy J. Farnham and David J. Segal. dCas9-based epigenome editing suggests acquisition of histone methylation is not sufficient for target gene repression. Nucleic Acids Research. 2017. DOI: 10.1093/nar/gkx578 (共同第一作者) (JCR: Q1, IF=11.561)

(5) Chonghua Ren#, Kun Xu#, Zhongtian Liu, Juncen Shen, Furong Han, Zhilong Chen, Zhiying Zhang. Dual-reporter surrogate systems for efficient enrichment of genetically modified cells. Cellular and Molecular Life Sciences. 2015. 72(14), p. 2773-4 (JCR: Q1, IF=6.721)

(6) Kun Xu#, Chonghua Ren#, Zhongtian Liu, Tao Zhang, Tingting Zhang, Duo Li, Ling Wang, Qiang Yan, Lijun Guo, Juncen Shen, Zhiying Zhang. Efficient genome engineering in eukaryotes using Cas9 from Streptococcus thermophilus. Cellular and Molecular Life Sciences. 72 (2) (2014), pp. 383–399 http://dx.doi.org/10.1007/s00018-014-1679-z (共同第一作者) (JCR: Q1, IF=6.721, 2014 Global Medical Discovery 'Key scientific article')

(7) Chonghua Ren#, Qiang Yan, Zhiying Zhang. Minimum length of direct repeat sequences required for efficient homologous recombination induced by zinc finger nuclease in yeast. Mol Biol Rep. 2014 Oct; 41(10):6939-48. doi: 10.1007/s11033-014-3579-6 (IF=2.024)

(8) Yichun Bai, Yang Liu, Zhenlei Su, Yana Ma, Chonghua Ren, Runzhen Zhao, Honglong Ji. Gene editing as a promising approach for respiratory diseases. Journal of Medical Genetics. 2017. 10.1136/jmedgenet-2017-104960 (IF=5.45)

(9) Simin Shao, Chonghua Ren, Zhongtian Liu, Yichun Bai, Zhilong Chen, Zehui Wei, Xin Wang, Zhiying Zhang, Kun Xu. Enhancing CRISPR/Cas9-mediated homology-directed repair in mammalian cells by expressing Saccharomyces cerevisiae Rad52. International Journal of Biochemistry and Cell Biology. 92 (2017) 43–52 (IF=3.9)

(10)Henriette O’Geen, Chonghua Ren, Nicole Coggins, David J. Segal. Unexpected binding behaviors of bacterial Argonautes in human cells cast doubts on their use as targetable gene regulators. Plos One. 2018. 13(3): e0193818. doi: 10.1371/journal. pone.0193818

(11) Yun Wu, Kun Xu, Chonghua Ren, Xinyi Li, Huijiao LU, Furong Han, Zehui Wei, Xin Wang, Zhiying Zhang. Enhanced CRISPR/Cas9-mediated biallelic gene editing with dual-surrogate reporter system. FEBS Letter. 2017. DOI: 10.1002/1873-3468.12599 (IF=3.519)

(12)Qiang Yan, Kun Xu, Jiani Xing, Tingting Zhang, Xin Wang, Zehui Wei, Chonghua Ren, Zhongtian Liu, Simin Shao, Zhiying Zhang. Multiplex CRISPR/Cas9-based genome engineering enhanced by Drosha-mediated sgRNA-shRNA structure. Scientific Reports. 2016. DOI: 10.1038/srep38970 (IF=5.228)

(13) Zhongtian Liu, Gang Zhou, Chonghua Ren, Kun Xu, Qiang Yan, Xinyi Li, Tingting Zhang, Zhiying Zhang. Oral administration of myostatin-specific recombinant Saccharomyces cerevisiae vaccine in rabbit. Vaccine. 2016. doi: 10.1016/j.vaccine.2016.03.036 (IF=3.413)

(14)刘素宁,李胜,任充华*.CRISPR系统用于昆虫基因表达调控的研究进展与展望. 昆虫学报。2018 61(12):1481-1487.

(15)任充华#,张婷婷,杨涵江,王昕,陈知龙,张智英. 人端粒酶逆转录酶(hRERT) 基因腺病毒载体的构建及包装. 西北农林科技大学学报(自然科学版)。2012, 40(7):39-43.

联系信息

地址:广东省广州市天河区中山大道西55号,华南师范大学生命科学学院昆虫所305室

Email:renchonghua111@scnu.edu.cn 或 renchonghua111@gmail.com

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