吴秀勇1，吴效明1，彭红军2，宁玉萍3，4，吴凯1，4*
( 1． 华南理工大学材料科学与工程学院生物医学工程系，广东广州510006; 2． 广州市脑科医院临床心理科，广东广州 510370) ; 3． 广州市脑科医院神经科，广东广州510370; 4． 广州市脑科医院－ 华工神经影像联合研究中心，广东广州 510370)
摘要: 抑郁症及焦虑障碍是常见、发病率高、危害性大的精神疾病，其临床诊断主要依靠临床观察、神经
心理学问卷调查等手段。近年来，磁共振成像及图像分析技术快速发展，可以定量化分析人脑的结构形
态及功能连接等，为阐明精神疾病的神经病理机制提供了新的研究思路和方法，也为临床诊断提供新的
客观证据和参考依据。本文综述了磁共振影像学在抑郁症、焦虑障碍以及抑郁症共病焦虑障碍等疾病
诊断中的应用，以及结构磁共振成像、弥散张量成像、静息态功能磁共振成像等技术的最新研究进展。
关键字: 磁共振影像; 抑郁症; 焦虑障碍

Advances in Magnetic Ｒesonance Imaging of Depression and Anxiety Disorders

Wu Xiuyong，Wu Xiaoming，
Peng Hongjun，Ning Yuping，Wu Kai． Space Medicine ＆ Medical Engineering，2015，28( 3) : 229 ～ 234
Abstract: Depression and anxiety disorders are common and harmful mental illnesses with high incidence．
The clinical diagnosis of these disorders relies on clinical observations，neuropsychological surveys，and other
means． Ｒecently，the technologies of magnetic resonance imaging ( MＲI) and image analysis have developed
rapidly． The quantitative analyses of structural morphology and functional connections of the human brain bring new methodologies to elucidate the neuropathlogical mechanisms of mental illnesses and also provide new evidences for clinical diagnosis． This paper reviewed the application of MＲI studies in depression，anxiety disorder，and depression comorbid with anxiety，as well as the advances of structural magnetic resonance imaging，diffusion tensor imaging，resting-state functional magnetic resonance imaging，and other technologies．
Key words: magnetic resonance imaging; depression; anxiety disorder